There's a new build tool around these days - cmake. Kde4 supposedly uses it, replacing the autotools configuration stuff. Now I can understand why someone would want to not use autotools - too complicated for many engineers to understand properly, and IMHO a pain in the a**.
Trolltech has a great tool already - qmake. Which is just as powerful in generating Makefiles. It can be used in large projects - namely, both Qt and Qtopia use it. Opie also uses qmake. I always thought it a bit odd that KDE does not use qmake.
Perhaps someone who knows both cmake and qmake can enlighten me on why any project should choose cmake over qmake?